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Unlock the Secrets of Malodor with Sequential's Cutting-Edge Microbiome Testing
Why Microbiome Testing for Malodor?
Malodor, or body odor, affects millions of people globally, with studies suggesting that up to 90% of individuals experience some form of body odor during their lifetime, especially in areas such as the underarms, feet, and groin (American Society for Microbiology). This issue arises primarily due to interactions between sweat and the skin’s microbiome, where certain bacteria, like Corynebacterium and Staphylococcus, break down sweat molecules into odorous compounds. The composition of a person’s microbiome greatly influences the severity and type of body odor they experience, which highlights the need for microbiome-focused deodorant formulations.
In vivo testing is crucial for deodorants because it allows scientists to see how the product affects both sweat production and the microbiome in real-world conditions. Without proper testing, deodorants might mask odors temporarily but disrupt the natural microbial balance, leading to skin irritation or increased malodour over time. By ensuring deodorants maintain a healthy microbiome, brands can create more effective, long-lasting solutions for body odor.
Sequential is leading the way in microbiome testing for the industry. With a specialized focus on skin conditions, we have developed an innovative solution tailored to help you understand the root causes of malodor at the microbial level. Our proprietary sequencing panel is designed specifically to offer in-depth analysis of malodor-associated microbiota, giving you the tools to transform skincare solutions.
Customized Analysis
Tailored insights specific to malodor, allowing your R&D team to develop more personalized and effective products.
Actionable Data
Leverage detailed reports to guide formulation decisions and validate product efficacy with precision.
Product Innovation
New deoderants or enhancing existing lines, our data helps you create targeted solutions with proven results.
Precision Sequencing
Target specific microbial communities associated with malodor.
Smart Probes™
Our dedicated team of scientists has developed a groundbreaking method for evaluating microbes through our Smart Probes™, a proprietary panel featuring 23 key microbes specifically identified as having the greatest impact on skin health, particularly in relation to malodor. To further investigate the complex relationship between body odor and the skin microbiome, we employ qPCR technology. This advanced technique enables us to precisely measure microbial populations on the skin, providing deeper insights into how imbalances in the microbiome contribute to malodor, such as the activity of bacteria like Corynebacterium and Staphylococcus. By carefully analyzing how deodorant and skincare products interact with odor-causing microbes, companies can develop solutions that not only target and reduce malodor but also support a healthy, balanced skin microbiome, ensuring long-lasting freshness and overall skin health.
Malodor Panel Targets
Corynebacterium species
These bacteria are known to break down sweat into fatty acids and other compounds that contribute to body odor. They are particularly prevalent in areas like the armpits.
Ågren MS, Ghathian KSA, Frederiksen AKS, Bjerrum MJ, Calum H, Danielsen PL, Menon J, Hædersdal M, Jorgensen LN. Zinc Oxide Inhibits Axillary Colonization by Members of the Genus Corynebacterium and Attenuates Self-perceived Malodour: A Randomized, Double-blind, Placebo-controlled Trial. Acta Derm Venereol. 2020 May 28;100(10):adv00145. doi: 10.2340/00015555-3499. PMID: 32399578; PMCID: PMC9137363.
Staphylococcus hominis
This bacterium is involved in the breakdown of sweat and the production of odor-causing compounds. It is commonly found in areas with high sweat gland activity.
Lam, T.H., Verzotto, D., Brahma, P. et al. Understanding the microbial basis of body odor in pre-pubescent children and teenagers. Microbiome 6, 213 (2018). https://doi.org/10.1186/s40168-018-0588-z
Cutibacterium acnes species
Although better known for its role in acne, this bacterium also contributes to body odor by metabolizing sweat and producing odoriferous substances.
Coenye T, Spittaels KJ, Achermann Y. The role of biofilm formation in the pathogenesis and antimicrobial susceptibility of Cutibacteriumacnes. Biofilm. 2021 Dec 9;4:100063. doi: 10.1016/j.bioflm.2021.100063. PMID: 34950868; PMCID: PMC8671523.
Industry Leader in Absolute Quantification
Sequential’s Smart Probe™ qPCR approach to microbiome analysis can resolve species and subspecies, giving statistically significant findings between skin conditions on in vivo human samples, compared to conventional sequencing approaches.
