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- Scalp Microbiome Testing | Sequential
Scalp Microbiome Testing As the scalp care industry grows, consumers demand transparency from the brands formulating their products. It has become essential for formulators to create products they are willing to test to present scientifically backed data-driven evidence of their products' true effects. Sequential offers microbiome testing for your scalp care formulations, ranging from scalp serums, shampoos, conditioners, oils, etc. We are dedicated to understanding how your product interacts with the scalp and its microbes. Depending on how in-depth you want to go, we offer qPCR, 16S, ITS, and Shotgun Metagenomics. Download Case Study! Personalized Approach to Testing Unlike other methodologies present within the industry, Sequential's approach ensures that your product's data and analysis will stand the test of industry regulations when they are introduced. You can tailor your study entirely to your unique requirements. Test Products in a Real-Life Context The microbiome comprises a complex ecosystem of microorganisms that live together in a delicate balance, which is why it's best to test directly upon it directly. To fully understand the impact a product is having on the microbiome, in vivo is the only way. Collect Longitudinal Data With in vivo testing we can design your study around the extended use of a product over multiple time points. This allows us to review how a product is performing before and after usage, but also take into account its gradual impact on the microbiome. Measure Against a Control Group Measure a product against a control group that might have a different percentage of your active ingredient within its formulation or no active at all. This will allow for deeper insights into the impact of a formulation on microbial balance and diversity. 4 Sequencing Reports To Pick From Depending on your development stage and what you are interested in studying we offer qPCR, 16S, ITS, and Shotgun Metagenomics. With our qPCR Smart Probes™ we can go down to the strain level in our analysis. Personalize Your Microbiome Study! Unlike hair, the scalp is formed of a living community of microorganisms such as bacterial and fungal players that can influence the balance of the scalp microbiome, even the subtlest of imbalances can lead to issues such as dandruff, itching, and irritation, resulting in unwanted flaking. Smart Probe s ™ Our dedicated team of scientists have developed a method of evaluating microbes through our Smart Probes ™ . These refer to a panel of 20 key microbes we have specifically identified as having the most impact on scalp health. Over and above the taxonomic characterisation that 16S offers, which gives us a snapshot of all the genus present within a collected sample (Cutibacterium , Staphylococcus , etc.) our targeted approach takes it a step further, opening the lens to the species (C. acnes ), sub-species (C. acnes defendens ) and even strains within them. This is a crucial distinction as not all strains of a species behave similarly. We find that within these species there are strains associated with inflammation and strains that are commensal, and beneficial. Gold Standard Certification Sequential has developed the gold standard test for products designed to target the microbiome, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. Using next-generation sequencing of the collection of micro-organisms found on the body, before and after product usage, Sequential investigates the microbial balance and diversity, and particular micro-organisms we know are important and play a role in a healthy microbiome. We give you an in vivo certification that your product maintains the microbiome. And it’s not exclusive to skincare! We do this for haircare products, oral products, and vulva/vaginal microbiomes. Personalize Your Microbiome Study! Supplement Your Microbiome Study Recruitment Services Let us take care of the entire candidate recruitment process for you! View More Biophysical Assessments Increase your data on the use of your product by evaluating additional biophysical factors. View More Formulation Support Seek consultation advice for your formulation if you are re-formulating or developing a new product. View More FAQ What is Sequential's testing platform? Sequential has developed the gold standard test for microbiome-friendly products, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. We offer a complete end-to-end solution to support microbiome-friendly claims. From consultancy and study design to our proprietary microbiome testing kits. We analyse, interpret and report our findings to meet your needs. Why is it necessary to test the microbiome in vivo? At present, there are no regulations for microbiome-related formulas that brands and formulators can follow, however, it has been universally acknowledged that the in vivo method of conducting clinical studies is becoming critical and paramount to getting marketing claims through. When regulations are introduced, which may be imminent, the in vitro system will find itself lacking, resulting in limited claims and certifications that do not hold their value. This is why, we at Sequential strive to offer an in vivo approach, knowing full well that we want our client's claims to be significantly backed by scientific and quantifiable data. What type of sequencing technology does Sequential use for analysis? We offer four types of sequencing techniques including qPCR with our Smart Probes™, 16S, ITS and Shotgun Metagenomics. Using next-generation sequencing of the collection of microorganisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome. Does Sequential offer claims certification for tested products? We provide our clients with a certification to claim “Maintains the Microbiome” subject to in vivo testing results which can be used in communication efforts. Once your product is tested with our qPCR Smart Probes™ and has shown favourable results in supporting the microbiome, we can certify your product with our Maintains the Microbiome certification seal. We have ensured that our seal and certification are backed by quantifiable data and scientifically significant markers. The aim is to ensure our clients feel confident in making their claims and can communicate the true benefit of their microbiome formulations.
- Sequential Alle Awards | Sequential
Allē Award: Sequential Wins Prestigious “Most Significant” Testing Method After being listed as a finalist as best ‘Claims testing methods & tools’ alongside Evonik, and XCellR8 - Sequential brings home top prize in C&T’s Allē Awards, 2022. The personal care and cosmetics industry in the US is valued at $190B. In the context of the skin microbiome, the industry is still a relatively nascent field. However, its projected growth is significant, estimated to grow at a compounded annual growth of 29.2% between 2022-2028. Owed to the impact of products on the skin microbiome, consumer awareness, and understanding that our microbiome is intimately linked to our health. Sequential is the B2B microbiome testing arm for Sequential Skin Ltd, which has developed the world’s first end-to-end platform for companies to evaluate their products on the microbiome in vivo. They specialize in skin, scalp and intimate area microbiome. "Of all the 'microbiome friendly' methodologies working to address both consumer and industry concerns about the impact of cosmetics on the microbiome, this is, in my opinion, the most quantitative and promising of the lot." – C&T's Allē Award judges, 2022. The company has developed a proprietary non-invasive method for collecting skin samples to analyze the skin microbiome using next-generation sequencing (NGS), with species and strain identification, in longitudinal (and clinical) studies. Services include data interpretation and the results are reported in a comprehensive, yet understandable format, ready for formulators and research scientists to incorporate into their product development pipeline. “The Allē Award gives us strong confidence in the testing platform and capabilities we’ve built in Sequential. Being the first to develop an in vivo microbiome test for the industry, we’re proud to see our hard work paying off” — Petronille Houdart, DPharm, skincare director at Sequential. About Sequential Sequential is part of the Sequential Skin group – with a US lab in New York City, alongside a lab in London and a lab in Singapore. Sequential team has over 20 years of combined expertise in genetics, epigenetics, and microbiome research. Sequential has validated its AI-driven testing platform with over 30 companies, analyzing over 12,000 skin microbiome samples. They specialise in skin, scalp and vulva/vaginal microbiome samples. They are supported by Enterprise SG, A*STAR, Genome Institute of Singapore, IndieBio New York, SOSV, Metaplanet Holdings, Scrum Ventures, Genedant VC, Ben Holmes (ex. General Partner at Index Ventures), Innovate UK, and are a resident company of Johnson & Johnson Innovation – JLABS.
- Targeted Microbiome Panels | Sequential
Our Targeted Microbiome Panels Sequential is proud to announce the launch of the industry's first-ever target panels, designed to address key skin concerns. These panels are the first of their kind, resulting from years of meticulous research by our scientists who have worked tirelessly to uncover the underlying microbial factors driving these conditions. Contrary to more traditional methods of studying the microbiome, Sequential’s panels offer a uniquely targeted approach, allowing clients to focus their research on specific areas of interest. Backed by a robust database of over 20,000 microbial samples and numerous studies, we are excited to bring this groundbreaking tool to our clients, paving the way for new insights and innovations in skincare. Discover More Discover More Discover More Discover More Discover More
- Vaginal Microbiome Testing | Sequential
Vaginal & Vulvar Microbiome Testing As the intimate care industry grows, consumers demand transparency from the brands formulating their products. It has become essential for formulators to create products they are willing to test to present scientifically backed data-driven evidence of their products' true effects. Sequential offers microbiome testing for your intimate care formulations, hygiene washes and other products geared towards that delicate area. We are dedicated to understanding how your product interacts with the vaginal region and its microbes. Depending on how in-depth you want to go, we offer qPCR, 16S, ITS, and Shotgun Metagenomics. Download Case Study! Personalized Approach to Testing Unlike other methodologies present within the industry, Sequential's approach ensures that your product's data and analysis will stand the test of industry regulations when they are introduced. You can tailor your study entirely to your unique requirements. Test Products in a Real-Life Context The microbiome comprises a complex ecosystem of microorganisms that live together in a delicate balance, which is why it's best to test directly upon it directly. To fully understand the impact a product is having on the microbiome, in vivo is the only way. Collect Longitudinal Data With in vivo testing we can design your study around the extended use of a product over multiple time points. This allows us to review how a product is performing before and after usage, but also take into account its gradual impact on the microbiome. Measure Against a Control Group Measure a product against a control group that might have a different percentage of your active ingredient within its formulation or no active at all. This will allow for deeper insights into the impact of a formulation on microbial balance and diversity. 4 Sequencing Reports To Pick From Depending on your development stage and what you are interested in studying we offer qPCR, 16S, ITS, and Shotgun Metagenomics. With our qPCR Smart Probes™ we can go down to the strain level in our analysis. Personalize Your Microbiome Study! The vaginal microbiome is a dynamic ecosystem primarily dominated by Lactobacillus bacteria, which produce lactic acid and help maintain an acidic pH, creating a hostile environment for potential pathogens. This acidic environment is crucial for preventing infections and promoting overall vaginal health. Smart Probe s ™ Our dedicated team of scientists have developed a method of evaluating microbes through our Smart Probes ™ . These refer to a panel of 20 key microbes we have specifically identified as having the most impact on vaginal health. Over and above the taxonomic characterisation that 16S offers, which gives us a snapshot of all the genus present within a collected sample (Lactobacillus , Streptococcus , etc.) our targeted approach takes it a step further, opening the lens to the species (L.crispatus ), sub-species and even strains within them. This is a crucial distinction as not all strains of a species behave similarly. In fact, we find that within these species there are strains associated with inflammation and strains that are commensal, and beneficial. Gold Standard Certification Sequential has developed the gold standard test for products designed to target the microbiome, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. Using next-generation sequencing of the collection of micro-organisms found on the body, before and after product usage, Sequential investigates the microbial balance and diversity, and particular micro-organisms we know are important and play a role in a healthy microbiome. We give you an in vivo certification that your product maintains the microbiome. And it’s not exclusive to skincare! We do this for haircare products, oral products, and vulva/vaginal microbiomes. Personalize Your Microbiome Study! Supplement Your Microbiome Study Recruitment Services Let us take care of the entire candidate recruitment process for you! View More Biophysical Assessments Increase your data on the use of your product by evaluating additional biophysical factors. View More Formulation Support Seek consultation advice for your formulation if you are re-formulating or developing a new product. View More FAQ What is Sequential's testing platform? Sequential has developed the gold standard test for microbiome-friendly products, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. We offer a complete end-to-end solution to support microbiome-friendly claims. From consultancy and study design to our proprietary microbiome testing kits. We analyse, interpret and report our findings to meet your needs. Why is it necessary to test the microbiome in vivo? At present, there are no regulations for microbiome-related formulas that brands and formulators can follow, however, it has been universally acknowledged that the in vivo method of conducting clinical studies is becoming critical and paramount to getting marketing claims through. When regulations are introduced, which may be imminent, the in vitro system will find itself lacking, resulting in limited claims and certifications that do not hold their value. This is why, we at Sequential strive to offer an in vivo approach, knowing full well that we want our client's claims to be significantly backed by scientific and quantifiable data. What type of sequencing technology does Sequential use for analysis? We offer four types of sequencing techniques including qPCR with our Smart Probes™, 16S, ITS and Shotgun Metagenomics. Using next-generation sequencing of the collection of microorganisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome. Does Sequential offer claims certification for tested products? We provide our clients with a certification to claim “Maintains the Microbiome” subject to in vivo testing results which can be used in communication efforts. Once your product is tested with our qPCR Smart Probes™ and has shown favourable results in supporting the microbiome, we can certify your product with our Maintains the Microbiome certification seal. We have ensured that our seal and certification are backed by quantifiable data and scientifically significant markers. The aim is to ensure our clients feel confident in making their claims and can communicate the true benefit of their microbiome formulations.
- Request a Study | Sequential
Start your Project Today! With our extensive database of more than 20,000 microbiome samples, we can gain valuable insights into the effectiveness of your formulations and personal care products. With our thorough research, we offer our clients actionable information and valuable insights. Our in vivo testing guarantees that your formulations are rigorously tested, providing you with measurable results for your personal care products.
- in vivo Microbiome Testing | Sequential
in vivo Sampling is the Future of Microbiome Testing We lead in clinical microbiome research and testing offering a comprehensive end-to-end platform designed to bring science-backed solutions to the personal care and pharma industry. We offer an expansive platform to conduct research on personal care products through microbiome testing, biophysical assessments, and offer full recruitment services for studies. We are keen to publish our findings with our partners to increase the literature within this space. At present our database of over 20,000 human microbiome samples is one of the most sophisticated within the industry and is growing rapidly. Skin Test your skincare products, ranging from facial cleansers, serums, moisturisers, and SPFs. Scalp Test your scalp care products ranging from scalp serums, oils, shampoos, and conditioners. Vaginal Test your intimate care products, ranging from washes, to hygiene sprays, and balms. Oral Test your oral care products ranging from mouth washes and toothpastes. Full End-To-End Testing Platform in vivo Study Design Collaborating closely with our clients to develop customised study protocols, ensuring that objectives are met with precision. Validated Collection Our non-invasive collection system consistently collects material for downstream analysis and allows for remote testing. Analysis & Reporting All analysis is carried out in-house allowing for a faster turn-around time on your study with exclusive access to our team of scientists and formulation experts. White Paper Publication Co-author a white paper with us based on the findings of your study to shorten the knowledge gap within the industry to demonstrate active's impact. Candidate Recruitment Carefully select human participants (location, age, etc.) to ensure the relevance and accuracy of the study. Microbiome Detection We offer four types of sequencing techniques including qPCR with our proprietary Smart Probes™, 16S, ITS and Shotgun Metagenomics. Claims Certification Providing comprehensive reports and certifications (Maintains the Microbiome seal) based on the study results which can be used in communication efforts. Co-Presentation We offer support by co-presenting at conferences where you want to demonstrate the impact of your study findings and explain the science behind the research. Start Your Clinical Study Today! State of the Art Sequencing Using next-generation sequencing of the collection of micro-organisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular micro-organisms we know are important and play a role in a healthy microbiome. With your pick from one of four sequencing reports, Sequential makes it easier to understand what depth of analysis is required for your particular needs. qPCR Microbiome (Bacteria+Fungi) Quantitative PCR (qPCR), also known as Real-Time PCR, is a method that Sequential uses in-house to measure the absolute number of copies of a microbial DNA defined by Sequential’s proprietary Smart Probes™. Using this method, we quantify the amount bacteria or fungi, allowing us to report level of species and strains within a given sample. The entire process is done at Sequential to ensure quality control, and extra control on your samples and privacy. Up Next-Generation Sequencing of ITS (total fungal population) ITS rRNA gene sequencing, or ITS amplicon sequencing is performed at Sequential to determine the relative abundance of taxa in a fungal community, and to compare between groups of interest. We know that fungi play a critical role in the microbiome of a healthy human, and it’s important to consider this application, especially for the scalp microbiome, and vaginal or vulva microbiome. We routinely offer two types of ITS rRNA primer regions: ITS1 & ITS2 Up Next-Generation Sequencing of 16S 16S rRNA gene sequencing, or 16S amplicon sequencing, is performed at Sequential to determine the relative abundance of taxa in a bacterial community, and to compare between groups of interest. This level of analysis can help to address changes in the overall bacterial profile over time or between treatment groups. We routinely offer two types of 16s rRNA primer regions: 16S V4 & 16S V1-V3 Up Shotgun Metagenomic Sequencing Shotgun metagenome sequencing is performed at Sequential for taxonomic profiling (diversity and abundance), as well as functional analysis across different organisms in a more exploratory approach. This complex technique allows for parallel sequencing of DNA from all organisms (bacterial, fungal, viral and human) within the community, with good coverage for species-level detection. The data generation allows for more advanced reporting and genome assemblies. Up FAQ What is Sequential's testing platform? Sequential has developed the gold standard test for microbiome-friendly products, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. We offer a complete end-to-end solution to support microbiome-friendly claims. From consultancy and study design to our proprietary microbiome testing kits. We analyse, interpret and report our findings to meet your needs. Why is it necessary to test the microbiome in vivo? At present, there are no regulations for microbiome-related formulas that brands and formulators can follow, however, it has been universally acknowledged that the in vivo method of conducting clinical studies is becoming critical and paramount to getting marketing claims through. When regulations are introduced, which may be imminent, the in vitro system will find itself lacking, resulting in limited claims and certifications that do not hold their value. This is why, we at Sequential strive to offer an in vivo approach, knowing full well that we want our client's claims to be significantly backed by scientific and quantifiable data. What type of sequencing technology does Sequential use for analysis? We offer four types of sequencing techniques including qPCR with our Smart Probes™, 16S, ITS and Shotgun Metagenomics. Using next-generation sequencing of the collection of microorganisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome. Does Sequential offer claims certification for tested products? We provide our clients with a certification to claim “Maintains the Microbiome” subject to in vivo testing results which can be used in communication efforts. Once your product is tested with our qPCR Smart Probes™ and has shown favourable results in supporting the microbiome, we can certify your product with our Maintains the Microbiome certification seal. We have ensured that our seal and certification are backed by quantifiable data and scientifically significant markers. The aim is to ensure our clients feel confident in making their claims and can communicate the true benefit of their microbiome formulations.
- Product Certification | Sequential
Global Leader for in vivo Microbiome Certification Create a World of Healthier Microbiomes In today's competitive market, it's crucial to find a unique selling point that sets your brand apart from the crowd. By harnessing the power of skin microbiome science, investing in in vivo testing, and obtaining the gold standard certification, you can create a competitive advantage that resonates with your customers. Gold Standard Certification Sequential is the gold standard for in vivo microbiome testing, using the most advanced analysis and sequencing technology to extract real and impactful conclusions. Global Testing Platform Having developed a testing platform that transcends continents, Sequential’s certification is globally recognised by academics, professionals and brands across the world. Human Microbiome Testing Sequential relies solely on the in vivo (in or on humans) approach due to the complex nature of the microbiome. The only meaningful way to test the microbiome is in vivo . Proprietary Microbiome Panel Having created a simpler approach to testing with our qPCR Smart Probes™, Sequential is able to measure the impact of a product against 20 key microbes down to strain level. Why is Certification Crucial? At present, there are no legal requirements when it comes to products claiming microbiome benefits. This is because the industry is still a young one, finding its footing and establishing its norms. As a result, Sequential has developed an in vivo testing approach with 25 minimum participants per group study to ensure that our studies are acknowledged at the strictest academic level. Unlike the in vitro approach, our in vivo certification is designed to demonstrate the true impact of all formulations in a real-life context on accurate application sites. Certify your Product Today! Rising Consumer Demand for Microbiome Supporting Formulations At Sequential, we have carried out significant market research on the demand for products claiming microbiome benefits. The results of our market research on over 3,500 participants found that 80% demand a customised microbiome-based skincare product that factors ethnicity, age, location and skin concerns. Moreover, 65% understand that the skin microbiome provides a protective barrier on the surface of their skin, and 60% would spend more on a skincare product that can positively impact their skin microbiome. (Sequential market research in 2019: 99% women, ages 18+) FAQ What is Sequential's testing platform? Sequential has developed the gold standard test for microbiome-friendly products, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. We offer a complete end-to-end solution to support microbiome-friendly claims. From consultancy and study design to our proprietary microbiome testing kits. We analyse, interpret and report our findings to meet your needs. Why is it necessary to test the microbiome in vivo? At present, there are no regulations for microbiome-related formulas that brands and formulators can follow, however, it has been universally acknowledged that the in vivo method of conducting clinical studies is becoming critical and paramount to getting marketing claims through. When regulations are introduced, which may be imminent, the in vitro system will find itself lacking, resulting in limited claims and certifications that do not hold their value. This is why, we at Sequential strive to offer an in vivo approach, knowing full well that we want our client's claims to be significantly backed by scientific and quantifiable data. What type of sequencing technology does Sequential use for analysis? We offer four types of sequencing techniques including qPCR with our Smart Probes™, 16S, ITS and Shotgun Metagenomics. Using next-generation sequencing of the collection of microorganisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome. Does Sequential offer claims certification for tested products? We provide our clients with a certification to claim “Maintains the Microbiome” subject to in vivo testing results which can be used in communication efforts. Once your product is tested with our qPCR Smart Probes™ and has shown favourable results in supporting the microbiome, we can certify your product with our Maintains the Microbiome certification seal. We have ensured that our seal and certification are backed by quantifiable data and scientifically significant markers. The aim is to ensure our clients feel confident in making their claims and can communicate the true benefit of their microbiome formulations.
- Sequential Skin - Skin Microbiome Test Kit - Skin Health Check
Sequential Skin has developed the first of its kind skin health test to discover the state of individuals' skin microbiome. People can now deep dive into their Skin Profile to figure out what their skin needs. Test your skin microbiome Benefits of your Skin Profile Skin Health Understand the state of your skin through your Skin Microbiome Balance Index score Skin Traits Learn about your skin traits through our in-app quiz and solutions for healthier skin Skin Age Discover your skin age and whether or not your skin is older/younger than you are Environment Unearth how your physical environment is impacting your skin microbiome Sample Register your kit: Register your kit on our Skin Health Tracker mobile app and answer the in-app quiz. Our Testing Technology Our microbiome test is the most comprehensive test on the market. We use a method known as quantitative real-time PCR (qPCR) that looks at specific markers in your skin microbiome and how they impact your skin. Our microbiome markers were generated in an ISO 13485 (medical devices) and CAP-accredited lab, ensuring the quality, accuracy and reliability of our results. Skin Health Testing Kit Partner with Sequential Skin to bring our innovative skin health test to your customers. Give them an in-depth analysis of what lies on the surface of their skin and how best to increase its overall wellbeing. Register your Interest What is Sequential's testing platform? Sequential has developed the gold standard test for microbiome-friendly products, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. We offer a complete end-to-end solution to support microbiome-friendly claims. From consultancy and study design to our proprietary microbiome testing kits. We analyse, interpret and report our findings to meet your needs. Why is it necessary to test the microbiome in vivo? At present, there are no regulations for microbiome-related formulas that brands and formulators can follow, however, it has been universally acknowledged that the in vivo method of conducting clinical studies is becoming critical and paramount to getting marketing claims through. When regulations are introduced, which may be imminent, the in vitro system will find itself lacking, resulting in limited claims and certifications that do not hold their value. This is why, we at Sequential strive to offer an in vivo approach, knowing full well that we want our client's claims to be significantly backed by scientific and quantifiable data. What type of sequencing technology does Sequential use for analysis? We offer four types of sequencing techniques including qPCR with our Smart Probes™, 16S, ITS and Shotgun Metagenomics. Using next-generation sequencing of the collection of microorganisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome. Does Sequential offer claims certification for tested products? We provide our clients with a certification to claim “Maintains the Microbiome” subject to in vivo testing results which can be used in communication efforts. Once your product is tested with our qPCR Smart Probes™ and has shown favourable results in supporting the microbiome, we can certify your product with our Maintains the Microbiome certification seal. We have ensured that our seal and certification are backed by quantifiable data and scientifically significant markers. The aim is to ensure our clients feel confident in making their claims and can communicate the true benefit of their microbiome formulations.
- Ingredients | Sequential
Category Ingredient What is it? Benefit Melanin Targeters Arbutin Arbutin is an antioxidant that is extracted from different berries. Arbutin helps in ensuring that skin is brightened and pigmentation is reduced in the skin. It can also fade scars. Hydrators Squalane Squalane is a hydrogenated version of squalene. It is an emollient and behaves similar to our own skin sebum. Prevents moisture loss, can neutralize UV damage . Postbiotics Lactobacillus ferment Lactobacillus ferment is a non-living probiotic ingredient made by fermentation of the microorganism Lactobacillus. Thanks to its soothing effect on the skin, it helps to strengthen the skin's defense and maintains the health of the skin microbiome. Allantoin Allantoin is an extract from comfrey plant. Allantoin protects and soothes the skin. Trehalose Trehalose is a disaccharide with hydrating properties for the skin. It’s a plant sugar. Trehalose is used as a prebiotic and is effective to help maintain healthy skin. Green Tea Extract Extract from the leaves of green tea. Tea Extracts is an antioxidant ingredient that aids soothing the skin and can also address skin discoloration and early signs of aging. Colloidal Oatmeal Colloidal Oatmeal is cocktail of oats that has been refined into powder and acts as a skin protectant. Colloidal Oatmeal aids in locking in moisture in the skin barrier and also has soothing properties. Skin Soothing Multi-Ceramide [Ceramide NP; Phytosphingosine] Ceramides are lipids or fats that exist in skin cells and make up to 40% of your outer skin layer. Ceramides are crucial in aiding your skin to retain moisture and prevent unwanted bacteria from entering your body. Skin Repairing Peptide Complex [copper tripeptide-1, Acetyl heaxapeptide-8, Palmitoyl Pentapepdide-4, Palmitoyl tripeptide-1, Palmitoyl tetrapepide-7, tripeptide-1, tripeptide-2, tripeptide-2, tripeptide-3, acetyl Octapeptide 3] Peptides are amino acid chains that aid in the forming of certain types of protein in the skin such as elastin and collagen. Peptides can help in increasing skin elasticity and reducing signs of aging, allowing skin to appear firmer. Skin Shields Vitamin E [Tocopherol] Tocopherol is an excellent example of a powerful antioxidant that is oil-soluble, meaning it can easily dissolve into the skin. Tocopherol helps in combating free-radical damage (such as pollution), and can also be an effective hydrator. Retinyl Palmitate Retinyl Palmitate is the most abundantly used form of retinol (Vitamin A). Retinyl Palmitate has anti-aging properties as well as anti-oxidant properties. Centella Asiatica Centella Asiatica is a medicinal herb that is known to treat inflammation and has antioxidant properties. Centella Asiatica is used as an active ingredient in skincare products for anti-inflammation, anti-oxidant and soothes compromised skin. Sorbitol Sorbitol is a sugar with hydrating properties that can nourish the probiotics that live on the skin allowing the skin microbiome to be balanced. Sorbitol breakdown by microorganisms on the skin creates beta-glucan, a skin calming antioxidant. Skin Barrier Protectors (Hydrators) Hyaluronic Acid Hyaluronic Acid is a humectant, meaning that it attracts water from the air or within the skin. Hyaluaronic Acid is one of the most common known ingredients for increasing overall moisture in skin. Vitamin C [Ascorbic Acid] Ascorbic Acid is an antioxidant and the most stable Vitamin C form. Ascorbic Acid aids in brightening the skin and aids in the production of collagen to prevent premature aging. Prebiotics Fructooligosaccharides Fructooligosaccharides is a prebiotic sugar used as food by the skin microbiota. It’s also a good source of antioxidants. It helps to keep the skin clean, hydrated, and well nutrified. It helps to maintain a healthy microbiome for your skin. Niacinamide Niacinamide is a vitamin that is water-soluble and penetrate into the skin with ease. Niacinamide aids in reducing the visibility of pores and removes dullness and restores the skin. Licorice Root Licorice Root is a plant based ingredients that can be cultivated in Asia, Europe, and in the Middle East. Licorice Root is a brightening agent in skincare products and can repair the skin. Lactic Acid Lactic Acid is a metabolic by-product released by the fermentation of microorganisms like lactobacillus. Lactic acid strengthens the skin barrier and has a positive impact on the skin microbiome balance. It also helps in reducing uneven tone and brightens skin tone.
- Privacy Policy | Sequential
Privacy Policy 1. Introduction 1.1 Important information and who we are Welcome to Sequential Skin Ltd’s Privacy and Data Protection Policy (“Privacy Policy”). At Sequential Skin Ltd (“we”, “us”, or “our”) we are committed to protecting and respecting your privacy and Personal Data in compliance with the United Kingdom General Data Protection Regulation (“GDPR”), the Data Protection Act 2018 and all other mandatory laws and regulations of the United Kingdom. This Privacy Policy explains how we collect, process and keep your data safe. The Privacy Policy will tell you about your privacy rights, how the law protects you, and inform our employees and staff members of all their obligations and protocols when processing data. The individuals from which we may gather and use data can include: Customers Suppliers Business contacts Employees/Staff Members Third parties connected to your customers Collaborators, academic institutes, industry partners. and any other people that the organisation has a relationship with or may need to contact. This Privacy Policy applies to all our employees and staff members and all Personal Data processed at any time by us. 1.2 Your Data Controller Sequential Skin Ltd is your Data Controller and responsible for your Personal Data. We are not obliged by the GDPR to appoint a data protection officer and have not voluntarily appointed one at this time. Therefore, any inquiries about your data should either be sent to us by email to team@sequential.bio or by post to 85 Great Portland Street, London, W1W 7LT, United Kingdom. You have the right to make a complaint at any time to the Information Commissioner’s Office (ICO), the UK supervisory authority for data protection issues (www.ico.org.uk ). We would, however, appreciate the chance to deal with your concerns before you approach the ICO so please contact us in the first instance. 1.3 Processing data on behalf of a Controller and processors’ responsibility to you In discharging our responsibilities as a Data Controller we have employees who will deal with your data on our behalf (known as “Processors”). The responsibilities below may be assigned to an individual or may be taken to apply to the organisation as a whole. The Data Controller and our Processors have the following responsibilities: Ensure that all processing of Personal Data is governed by one of the legal bases laid out in the GDPR (see 2.2 below for more information); Ensure that Processors authorised to process Personal Data have committed themselves to confidentiality or are under an appropriate statutory obligation of confidentiality; Implement appropriate technical and organisational measures to ensure a level of security appropriate to the risk associated with the processing of Personal Data; Obtain the prior specific or general authorisation of the Controller before engaging another Processor; Assist the Controller in the fulfilment of the Controller's obligation to respond to requests for exercising the data subject's rights; Make available to the Controller all information necessary to demonstrate compliance with the obligations laid down in the GDPR and allow for and contribute to audits, including inspections, conducted by the Controller or another auditor mandated by the Controller; Maintain a record of all categories of processing activities carried out on behalf of a Controller; Cooperate, on request, with the supervisory authority in the performance of its tasks; Ensure that any person acting under the authority of the Processor who has access to Personal Data does not process Personal Data except on instructions from the Controller; and Notify the Controller without undue delay after becoming aware of a Personal Data Breach. 2. Legal Basis for Data Collection 2.1 Types of data / Privacy policy scope “Personal Data” means any information about an individual from which that person can be identified. It does not include data where the identity has been removed (anonymous data). We may collect, use, store and transfer different kinds of Personal Data about you which we have grouped together below. Not all of the following types of data will necessarily be collected from you but this is the full scope of data that we collect and when we collect it from you: Profile/Identity Data: This is data relating to your first name, last name, gender, date of birth. Contact Data: This is data relating to your phone number, addresses, email addresses, phone numbers. Marketing and Communications Data: This is your preferences in receiving marketing information and other information from us. Technical Data: This is your IP address, browser type and version, time zone setting and location, operating system and platform, and other technology on the devices you use to engage with us. Customer Support Data: This includes feedback and survey responses. Usage Data: information about how you use our website, products and services. We do not collect any Special Categories of Personal Data about you (this includes details about your race or ethnicity, religious or philosophical beliefs, sex life, sexual orientation, political opinions, trade union membership, information about your health, and genetic and biometric data). Nor do we collect any information about criminal convictions and offences. 2.2 The Legal Basis for Collecting That Data There are a number of justifiable reasons under the GDPR that allow collection and processing of Personal Data. The main avenues we rely on are: “Consent”: Certain situations allow us to collect your Personal Data, such as when you tick a box that confirms you are happy to receive email newsletters from us, or ‘opt in’ to a service. “Contractual Obligations”: We may require certain information from you in order to fulfil our contractual obligations and provide you with the promised service. “Legal Compliance”: We’re required by law to collect and process certain types of data, such as fraudulent activity or other illegal actions. “Legitimate Interest”: We might need to collect certain information from you to be able to meet our legitimate interests - this covers aspects that can be reasonably expected as part of running our business, that will not have a material impact on your rights, freedom or interests. Examples could be your address, so that we know where to deliver something to, or your name, so that we have a record of who to contact moving forwards. 3. How We Use your Personal Data 3.1 Our data uses We will only use your Personal Data when the law allows us to. Set out below is a table containing the different types of Personal Data we collect and the lawful basis for processing that data. Please refer to section 2.2 for more information on the lawful basis listed in the table below. Examples provided in the table below are indicative in nature and the purposes for which we use your data may be broader than described but we will never process your data without a legal basis for doing so and it is for a related purpose. For further inquiries please contact us. 3.2 Marketing and content updates You will receive marketing and new content communications from us if you have created an account and chosen to opt into receiving those communications. From time to time we may make suggestions and recommendations to you about goods or services that may be of interest to you. 3.3 Change of purpose We will only use your Personal Data for the purposes for which we collected it, unless we reasonably consider that we need to use it for another reason and that reason is compatible with the original purpose. If you wish to get an explanation as to how the processing for the new purpose is compatible with the original purpose, please contact us. If we need to use your Personal Data for an unrelated purpose, we will notify you and we will explain the legal basis which allows us to do so. Please note that we may process your Personal Data without your knowledge or consent, in compliance with the above rules, where this is required or permitted by law. 4. Your Rights and How You Are Protected By Us 4.1 Your Legal Rights Under certain circumstances, you have the following rights under data protection laws in relation to your personal data: Right to be informed. You have a right to be informed about our purposes for processing your personal data, how long we store it for, and who it will be shared with. We have provided this information to you in this policy. Right of access. This enables you to receive a copy of the personal data we hold about you and to check that we are lawfully processing it (also known as a "data subject access request"). See section 4.4 below for more details on how you can make a data subject access request. Right to rectification. You have a right to request correction of the personal data that we hold about you. This enables you to have any incomplete or inaccurate data we hold about you corrected, though we may need to verify the accuracy of the new data you provide to us. Right to erasure. You have the right to ask us to delete or remove personal data where there is no good reason for us continuing to process it, where you have successfully exercised your right to object to processing (see below), where we may have processed your information unlawfully or where we are required to erase your personal data to comply with local law. Note, however, that we may not always be able to comply with your request of erasure for specific legal reasons which will be notified to you, if applicable, at the time of your request. Right to object. You can object to the processing of personal data we hold about you. This effectively allows you to stop or prevent us from processing your personal data. Note that this is not an absolute right and it only applies in certain circumstances, for example: (i) Where we are processing your personal data for direct marketing purposes. (ii) Where we are relying on a legitimate interest (or those of a third party) and there is something about your particular situation which makes you want to object to processing on this ground as you feel it impacts on your fundamental rights and freedoms. (iii) In some cases, we may continue processing your data if we can demonstrate that we have compelling legitimate grounds to process your information which override your rights and freedoms. Right to restrict processing. You have the right to request the restriction or suppression of their personal data. Note that this is not an absolute right and it only applies in certain circumstances: (i) If you want us to establish the data's accuracy. (ii) Where our use of the data is unlawful but you do not want us to erase it. (iii) Where you need us to hold the data even if we no longer require it as you need it to establish, exercise or defend legal claims. (iv) You have objected to our use of your data but we need to verify whether we have overriding legitimate grounds to use it. Right to data portability. You have the right to request the transfer of your personal data to you or to a third party. If you make such a request, we will provide to you, or a third party you have chosen, your personal data in a structured, commonly used, machine-readable format. Note that this right only applies to automated information which you initially provided consent for us to use or where we used the information to perform a contract with you. If you wish to make a request under any of these rights, please contact us at team@sequential.bio . 4.2 How Sequential Skin Ltd protects customers' Personal Data We are concerned with keeping your data secure and protecting it from inappropriate disclosure. We implement a variety of security measures to ensure the security of your Personal Data on our systems, including We implement certain security measures to ensure the security of your Personal Data on our systems, including using encrypted servers that gives confidence that personal data is being treated securely.. Any Personal Data collected by us is only accessible by a limited number of employees who have special access rights to such systems and are bound by obligations of confidentiality. If and when we use subcontractors to store your data, we will not relinquish control of your Personal Data or expose it to security risks that would not have arisen had the data remained in our possession. However, unfortunately no transmission of data over the internet is guaranteed to be completely secure. It may be possible for third parties not under the control of Sequential Skin Ltd to intercept or access transmissions or private communications unlawfully. While we strive to protect your Personal Data, we cannot ensure or warrant the security of any Personal Data you transmit to us. Any such transmission is done at your own risk. If you believe that your interaction with us is no longer secure, please contact us. 4.3 Opting out of marketing promotions You can ask us to stop sending you marketing messages at any time by unsubscribing at the bottom of the email. Where you opt out of receiving these marketing messages, we will continue to retain other Personal Data provided to us as a result of interactions with us not related to your marketing preferences. 4.4 How to request your data and the process for obtaining it You will not have to pay a fee to access your Personal Data (or to exercise any of the other rights). However, if your request is clearly unfounded, we could refuse to comply with your request. We may need to request specific information from you to help us confirm your identity and ensure you have the right to access your Personal Data (or to exercise any of your other rights). This is a security measure to ensure that Personal Data is not disclosed to any person who has no right to receive it. We may also contact you to ask you for further information in relation to your request to speed up our response. 5. Your Data and Third Parties 5.1 Sharing your data with third parties We may share non-Personal Data with third parties. We may share your Personal Data with subcontractors or affiliates, subject to confidentiality obligations to use it only for the purposes for which we disclose it to them and pursuant to our instructions. We may also share Personal Data with interested parties in the event that Sequential Skin Ltd anticipates a change in control or the acquisition of all or part of our business or assets or with interested parties in connection with the licensing of our technology. If Sequential Skin Ltd is sold or makes a sale or transfer, we may, in our sole discretion, transfer, sell or assign your Personal Data to a third party as part of or in connection with that transaction. Upon such transfer, the Privacy Policy of the acquiring entity may govern the further use of your Personal Data. In all other situations your data will still remain protected in accordance with this Privacy Policy (as amended from time to time). We may share your Personal Data at any time if required for legal reasons or in order to enforce our terms or this Privacy Policy. 5.2 Third-Party Links This Site may include links to third-party websites, plug-ins and applications. Clicking on those links or enabling those connections may allow third parties to collect or share data about you. We do not control these third-party websites and are not responsible for their privacy statements. When you leave our Site, we encourage you to read the privacy policy of every website you visit. 6. How Long We Retain Your information We will only retain your Personal Data for as long as reasonably necessary to fulfil the purposes we collected it for. We may retain your Personal Data for a longer period than usual in the event of a complaint or if we reasonably believe there is a prospect of litigation in respect to our relationship with you. 7. International Transfer of Data Your information may be stored and processed in the US or other countries or jurisdictions outside the US where Sequential Skin Ltd has facilities. By using Sequential Skin Ltd, you are permitting and consenting to the transfer of information, including Personal Data, outside of the US. 8. Notification of Changes and Acceptance of Policy We keep our Privacy Policy under review and will place any updates here. This version is dated 23 February 2024. By using Sequential Skin Ltd, you consent to the collection and use of data by us as set out in this Privacy Policy. Continued access or use of Sequential Skin Ltd will constitute your express acceptance of any modifications to this Privacy Policy. 9. Interpretation All uses of the word "including" mean "including but not limited to" and the enumerated examples are not intended to in any way limit the term which they serve to illustrate. Any email addresses set out in this policy may be used solely for the purpose for which they are stated to be provided, and any unrelated correspondence will be ignored. Unless otherwise required by law, we reserve the right to not respond to emails, even if they relate to a legitimate subject matter for which we have provided an email address. You are more likely to get a reply if your request or question is polite, reasonable and there is no relatively obvious other way to deal with or answer your concern or question (e.g. FAQs, other areas of our website, etc.). Our staff are not authorised to contract on behalf of Sequential Skin Ltd, waive rights or make representations (whether contractual or otherwise). If anything contained in an email from a Sequential Skin Ltd address contradicts anything in this policy, our terms or any official public announcement on our website, or is inconsistent with or amounts to a waiver of any Sequential Skin Ltd rights, the email content will be read down to grant precedence to the latter. The only exception to this is genuine correspondence expressed to be from the Sequential Skin Ltd legal department.
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The skin health tracker Benefit of your personal Skin Health Tracker Download your personal Skin Health Tracker app to receive your microbiome test results and unlock personalized skincare tips. Results Skin Profile Receive your comprehensive skin microbiome sample results. Results Accessibility Access to your Skin Profile results in the palm of your hand. Results Unlock Our Expertise Learn skincare tips to help you with your own perceived skin traits. Results Discover Learn more about the skin microbiome through our Discover articles. What is Sequential's testing platform? Sequential has developed the gold standard test for microbiome-friendly products, in vivo (in, or on, humans). Finally, we can give some certainty about if a product is truly affecting the microbiome. We offer a complete end-to-end solution to support microbiome-friendly claims. From consultancy and study design to our proprietary microbiome testing kits. We analyse, interpret and report our findings to meet your needs. Why is it necessary to test the microbiome in vivo? At present, there are no regulations for microbiome-related formulas that brands and formulators can follow, however, it has been universally acknowledged that the in vivo method of conducting clinical studies is becoming critical and paramount to getting marketing claims through. When regulations are introduced, which may be imminent, the in vitro system will find itself lacking, resulting in limited claims and certifications that do not hold their value. This is why, we at Sequential strive to offer an in vivo approach, knowing full well that we want our client's claims to be significantly backed by scientific and quantifiable data. What type of sequencing technology does Sequential use for analysis? We offer four types of sequencing techniques including qPCR with our Smart Probes™, 16S, ITS and Shotgun Metagenomics. Using next-generation sequencing of the collection of microorganisms found on the body, during product usage, Sequential investigates the microbial diversity, and particular microorganisms we know are important and play a role in a healthy microbiome. Does Sequential offer claims certification for tested products? We provide our clients with a certification to claim “Maintains the Microbiome” subject to in vivo testing results which can be used in communication efforts. Once your product is tested with our qPCR Smart Probes™ and has shown favourable results in supporting the microbiome, we can certify your product with our Maintains the Microbiome certification seal. We have ensured that our seal and certification are backed by quantifiable data and scientifically significant markers. The aim is to ensure our clients feel confident in making their claims and can communicate the true benefit of their microbiome formulations. Unearth the secrets of your microbiome