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Chemical peels are dermatological procedures that involve applying a chemical solution to the skin, thereby exfoliating the top layers to allow cell turnover and enhance skin texture and tone. The process involves using different types of acids or chemical agents that can vary in strength, leading to varying depths of peel, from superficial to deep. The procedure needs to be carried out more than once to get beneficial results, and recent research has begun to explore their impact on the skin microbiome.
What we know:
Chemical peels can reduce sebum production and possess antibacterial, anti-inflammatory, keratolytic, and comedolytic properties (Măgerușan et al., 2023).
30% Supramolecular Salicylic Acid Peel have shown to decrease certain bacterial populations such as Staphylococcus and Propionibacterium (Shao et al., 2023).
A study had found out that the immediate application of the chemical peel, caused a disruption in the skin's microbial composition. However, over a period of several weeks, the skin microbiota had rebalanced to levels similar or better than pre-treatment levels, indicating a temporary disturbance followed by a recovery phase (Bhardwaj et al., 2024).
It was seen that immediately after the peel, C. acnes decreased by 60%. However, within two weeks, these counts began to return to normal levels, reaching baseline levels by the fourth week (Bhardwaj et al., 2024).
Although the peel initially compromises the skin barrier, the recovery phase showed an improvement in barrier function, potentially due to the regrowth of a balanced microbiome (Bhardwaj et al., 2024).
Industry impact & potential:
Post-peel treatments should be designed to restore and support the skin microbiome.
Further studies need to be done to delve deeper into the interaction between chemical peels and skin microbiome.
Our solution:
Sequential is at the forefront of integrating microbiome science into skincare. Our cutting-edge research aims to analyse and understand how skincare products interact with the skin microbiome. By collaborating with us and our skincare professionals we can advise you on treatments that not only enhance skin appearance but also maintain microbiome health.
Reference:
Bhardwaj V, Handler MZ, Mao J, Azadegan C, Panda PK, Breunig HG, Wenskus I, Diaz I, König
K. A novel professional-use synergistic peel technology to reduce visible hyperpigmentation on face: Clinical evidence and mechanistic understanding by computational biology and optical biopsy. Exp Dermatol. 2024 Apr;33(4):e15069. doi: 10.1111/exd.15069. PMID: 38568090.
Măgerușan ȘE, Hancu G, Rusu A. A Comprehensive Bibliographic Review Concerning
the Efficacy of Organic Acids for Chemical Peels Treating Acne Vulgaris. Molecules. 2023 Oct 22;28(20):7219. doi: 10.3390/molecules28207219. PMID: 37894698; PMCID: PMC10608815.
Shao X, Chen Y, Zhang L, Zhang Y, Ariyawati A, Chen T, Chen J, Liu L, Pu Y, Li Y, Chen J.
Effect of 30% Supramolecular Salicylic Acid Peel on Skin Microbiota and Inflammation in Patients with Moderate-to-Severe Acne Vulgaris. Dermatol Ther (Heidelb). 2023 Jan;13(1):155-168. doi: 10.1007/s13555-022-00844-5. Epub 2022 Nov 9. PMID: 36350527; PMCID: PMC9823178.
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