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How can personalisation be used to develop products that maintain the microbiome?


How can personalisation be used to develop products that maintain the microbiome?


Several industries have begun looking to the use of personalisation to improve the efficacy and targeting of their products or services. Cosmetic brands can embrace this practice when developing products that maintain the microbiome to improve customer satisfaction, and gain a competitive advantage while supporting and sustaining a healthy microbiome.


Outline of research:

  • A survey conducted on 1,038 adults in the U.S. found 75% of shoppers would pay more for a personalised shopping experience (Bolt, 2023)

  • The personalised beauty space received 1.04 billion U.S. dollars worth of investment in 2021, its size is projected to increase to 63.34 billion dollars by 2027 (Statista 2021; GlobeNewswire, 2023)

  • The skin microbiome varies across individuals, some of the factors include: age, sex, geographical location, and genetics (Russo et al., 2023; Kim et al., 2021; Robert et al., 2022; Gupta et al., 2017; Si et al., 2015; Wang et al., 2021)

  • Use of certain skin care products can shift the microbiome away from its natural composition, giving rise to disorders like dermatitis by altering the microenvironments inhabited by these populations (Bouslimani et al., 2019)

  • Microbiome personalisation can promote the use of formulations that prioritise fermented ingredients, extracts, ceramides, and prebiotics to nourish the good bacteria of the microbiome (Dolečková et al., 2020)

  • Determining the specific microbiome composition of skin can be used to optimise products that help control or alleviate the symptoms of dysbiotic skin disorders through the inclusion of ingredients that reduce or prevent the growth of microbes driving these conditions (Collins 2023)


Industry impact and potential:

More brands are considering the importance of microbiome personalisation when formulating their products. Gallinee (an industry partner of Sequential) is one of the major drivers of this philosophy through their at-home microbiome testing kit that gives consumers an in-depth breakdown and report of their skin microbiome, allowing them to make detailed personalised choices regarding their skincare routines based on their microbiomes need.


Our solution:

  • We have partnered with several companies seeking to increase the level of personalisation for their products, including industry leaders such as Gallinée Microbiome Skincare and Shiseido, to provide Gold Standard Certification for your products.

  • Our invivo microbiome testing platform and extensive database of 18,000+ samples provides a detailed assessment of how your product interacts with, and influences the skin microbiome, and other regions of the body like the scalp, mouth, and vaginal microbiome.

  • We also provide formulation support for your personalised skin care products, ensuring its ingredients match the needs of what your product seeks to deliver.

References:

Bolt. (2023, May 31). 75% of shoppers would pay more for beauty products to get personalized online shopping experiences, says new survey. PR Newswire. Retrieved from https://www.prnewswire.com/news-releases/75-of-shoppers-would-pay-more-for-beauty-products-to-get-personalized-online-shopping-experiences-says-new-survey-301837863.html


Bouslimani A, da Silva R, Kosciolek T, Janssen S, Callewaert C, Amir A, Dorrestein K, Melnik AV, Zaramela LS, Kim JN, Humphrey G, Schwartz T, Sanders K, Brennan C, Luzzatto-Knaan T, Ackermann G, McDonald D, Zengler K, Knight R, Dorrestein PC. The impact of skin care products on skin chemistry and microbiome dynamics. BMC Biol. 2019 Jun 12;17(1):47. doi: 10.1186/s12915-019-0660-6. PMID: 31189482; PMCID: PMC6560912.


Collins SL, Stine JG, Bisanz JE, Okafor CD, Patterson AD. Bile acids and the gut microbiota: metabolic interactions and impacts on disease. Nat Rev Microbiol. 2023 Apr;21(4):236-247. doi: 10.1038/s41579-022-00805-x. Epub 2022 Oct 17. PMID: 36253479.


Dolečková, Iva & Čápová, Aneta & Machková, Lenka & Moravčíková, Soňa & Marešová, Markéta & Velebný, Vladimír. (2020). Seasonal variations in the skin parameters of Caucasian women from Central Europe. Skin Research and Technology. 27. 10.1111/srt.12951. 


GlobeNewswire (2023). Global next-generation personalized beauty market to reach $63.34 billion by 2027. Retrieved from https://www.globenewswire.com/fr/news-release/2023/07/04/2698923/0/en/Global-Next-Generation-Personalized-Beauty-Market-to-Reach-63-34-Billion-by-2027.html


Gupta VK, Paul S, Dutta C. Geography, Ethnicity or Subsistence-Specific Variations in Human Microbiome Composition and Diversity. Front Microbiol. 2017 Jun 23;8:1162. doi: 10.3389/fmicb.2017.01162. PMID: 28690602; PMCID: PMC5481955.


Kim, JH., Son, SM., Park, H. et al. Taxonomic profiling of skin microbiome and correlation with clinical skin parameters in healthy Koreans. Sci Rep 11, 16269 (2021). https://doi.org/10.1038/s41598-021-95734-9


Robert C, Cascella F, Mellai M, Barizzone N, Mignone F, Massa N, Nobile V, Bona E. Influence of Sex on the Microbiota of the Human Face. Microorganisms. 2022; 10(12):2470. https://doi.org/10.3390/microorganisms10122470


Russo E, Di Gloria L, Cerboneschi M, Smeazzetto S, Baruzzi GP, Romano F, Ramazzotti M, Amedei A. Facial Skin Microbiome: Aging-Related Changes and Exploratory Functional Associations with Host Genetic Factors, a Pilot Study. Biomedicines. 2023 Feb 23;11(3):684. doi: 10.3390/biomedicines11030684. PMID: 36979663; PMCID: PMC10045008.


Si J, Lee S, Park JM, Sung J, Ko G. Genetic associations and shared environmental effects on the skin microbiome of Korean twins. BMC Genomics. 2015 Nov 23;16:992. doi: 10.1186/s12864-015-2131-y. PMID: 26596276; PMCID: PMC4657342.


Statista. (2021). Global investment in personalized beauty from 2010 to 2021. https://www.statista.com/statistics/1268261/personalized-beauty-investment-worldwide/


Wang L, Xu YN, Chu CC, Jing Z, Chen Y, Zhang J, Pu M, Mi T, Du Y, Liang Z, Doraiswamy C, Zeng T, Wu J, Chen L. Facial Skin Microbiota-Mediated Host Response to Pollution Stress Revealed by Microbiome Networks of Individual. mSystems. 2021 Aug 31;6(4):e0031921. doi: 10.1128/mSystems.00319-21. Epub 2021 Jul 27. PMID: 34313461; PMCID: PMC8407115.

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